REJURAN contains up to 4 times the concentration of polynucleotides per 20 mg per 1 mL compared to competing products.
Polynucleotides for skin that needs to be renewed from within
Polynucleotides help improve skin quality from the inside out—gently, gradually, and naturally.
A regenerative treatment that improves skin quality.
Polynucleotide treatments are among the most sought-after regenerative treatments in modern aesthetic medicine. They are suitable for skin that does not need more volume, but rather more regeneration. It helps when the skin looks tired, has lost its elasticity, has a deteriorated texture, or needs support to recover from acne, scars, or natural aging.
Unlike fillers, polynucleotides do not alter facial contours. And unlike botulinum toxin, they do not affect muscles or facial expressions. Their role is to support the skin’s natural regenerative processes and gradually improve its hydration, firmness, elasticity, and overall quality.
Results don't happen overnight. The skin renews itself gradually, naturally, and from within. That's why the effect is subtle, unobtrusive, and very natural. Your skin will look smoother, fresher, firmer, and healthier without altering your features.
At BeautyLab , we use the proven REJURAN® and PLINEST® formulations . Which one is better suited for you depends on your skin condition, the treatment area, your expectations, and the level of regeneration your skin needs.
Polynucleotides that promote natural regeneration
Book an appointment at BeautyLab for a treatment that will improve your skin's quality, hydration, and natural renewal.
Who Should Use Polynucleotides?
Polynucleotides aren't just for skin showing visible signs of aging. They're suitable for anyone who wants to improve their skin's quality, support its regeneration and hydration, and enhance its natural firmness.
We often recommend them for skin that looks tired, dull, or has lost its natural radiance. They can also help if you notice fine lines, a rough texture, loss of elasticity, or the feeling that your skin no longer responds to your usual at-home skincare routine the way it used to.
Polynucleotides are also suitable for the eye area, which may appear tired regardless of how much sleep you get, as well as for thin skin under the eyes or fine lines. In the case of acne scars or minor skin imperfections, they can support the skin’s natural regeneration and gradually improve its texture.
If you're not sure whether polynucleotides are the right choice for you, we'll be happy to explain everything during a consultation. We'll assess your skin and your expectations, and recommend a solution that makes sense for you.
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REJURAN® Polynucleotides - Regeneration of the Eye Area
REJURAN® is a regenerative treatment for the eye area containing polynucleotides at a concentration of 20 mg/ml. It helps promote the renewal of the delicate skin under the eyes and improve its hydration, elasticity, and overall quality.
It is suitable for a tired appearance, fine lines, thin skin, or a loss of radiance around the eyes. The result is not a change in facial expression, but a gradual improvement in the skin, which appears more rested, smoother, and naturally healthier.
PLINEST® Polynucleotides - Regeneration of the Eye Area
PLINEST® is a regenerative treatment for the eye area that contains polynucleotides. It helps promote natural skin renewal, collagen production, hydration, and firmness in the delicate skin under the eyes.
It is ideal for a tired appearance, fine lines, loss of elasticity, or poor skin texture. The result is a gradual smoothing of the eye area and skin that looks fresher, smoother, and more natural.
REJURAN® Polynucleotides - Scar Regeneration
REJURAN® is a regenerative treatment containing polynucleotides at a concentration of 20 mg/ml. It helps promote skin renewal, hydration, elasticity, and an improvement in overall skin quality.
For acne scars or minor skin imperfections, it can help gradually smooth the skin’s texture and support its natural regeneration. The result is skin that looks smoother, firmer, and healthier.
REJURAN® Polynucleotides - Skin Regeneration
REJURAN® is a regenerative treatment containing polynucleotides at a concentration of 20 mg/ml. It helps promote skin renewal, hydration, elasticity, and overall skin quality.
It is suitable for tired, weakened, or mature skin that needs to boost regeneration and regain its radiance. The result is a gradual improvement in the skin’s texture, firmness, and natural appearance.
PLINEST® Polynucleotides - Skin Regeneration
PLINEST® is a regenerative treatment containing polynucleotides that support the skin’s natural renewal, collagen production, hydration, and firmness.
It is suitable for tired, weakened, or mature skin that needs to boost regeneration and improve its texture. The result is skin that gradually becomes smoother, fresher, and naturally more vibrant.
In the hands of experts who understand beauty
MUDr. Marta Javor
Dermatologist and Venereologist
Jana PinČeková
Nurse
Bronislava Bálent
Esthederm Institute
Karin Dubravay
Skin Expert
MUDr. Katarína Valentová
Aesthetic Medicine Physician
MUDr. Katarína Bieliková
Laser Medicine Specialist
MUDr. Sabina Lauková
Aesthetic Medicine Physician
MUDr. Ivana Chválna
Gynecologist | Intimate Medicine
Andrea Trnkusová
Nurse
What People Have Said About Us
Price List for Polynucleotide Application
REJURAN® Polynucleotides - Regeneration of the Eye Area
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REJURAN® Polynucleotides – Regeneration of the Eye Area Time: 30 min |
290€
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PLINEST® Polynucleotides - Regeneration of the Eye Area
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PLINEST® Polynucleotides – Regeneration of the Eye Area
PLINEST® provides targeted skin renewal at the cellular level. Polynucleotides support natural collagen production, improve the skin’s quality, firmness, and hydration, while ensuring a comfortable treatment experience and visibly refining the skin’s texture.
Time: 30 min |
190€ |
REJURAN® Polynucleotides - Scar Regeneration
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REJURAN® Polynucleotides – Scar Regeneration REJURAN contains up to 4 times the concentration of polynucleotides per 20 mg per 1 mL compared to competing products. Time: 30 min |
290€ |
REJURAN® Polynucleotides - Skin Regeneration
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REJURAN® Polynucleotides – Skin Regeneration REJURAN® contains up to 4 times the concentration of polynucleotides per 1 ml at a dose of 20 mg compared to competing products. Time: 1h30min |
350€ |
PLINEST® Polynucleotides - Skin Regeneration
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PLINEST® Polynucleotides – Skin Regeneration PLINEST® provides targeted skin renewal at the cellular level. Polynucleotides support natural collagen production, improve the skin’s quality, firmness, and hydration, while ensuring a comfortable treatment experience and visibly refining the skin’s texture.
Time: 1h30min |
200€ |
FAQ: Frequently Asked Questions About Polynucleotides
What is the difference between REJURAN® and PLINEST®?
Both REJURAN® and PLINEST® are treatments containing polynucleotides that support the skin’s natural regeneration, hydration, firmness, and overall quality. REJURAN® is suitable for cases requiring more intensive regeneration, such as scars, poor skin texture, or the sensitive area around the eyes. PLINEST® is a gentler and more affordable alternative for improving skin quality, elasticity, and hydration. We’ll recommend which treatment is best for you during your consultation.
Does polynucleotide treatment hurt?
The treatment is administered using fine needles, and most clients describe it as a slight pinch or pressure. For more sensitive areas, we can use an anesthetic cream to make the treatment more comfortable.
When will I see results after the polynucleotide treatment?
Polynucleotides do not produce an immediate “before and after” effect. The first changes usually appear after 2–4 weeks. The skin may gradually appear more hydrated, firmer, smoother, and healthier. The results develop naturally, as skin regeneration takes time.
How many polynucleotide treatments do I need?
We most often recommend a series of 2–3 treatments spaced 3–4 weeks apart. The exact number depends on the condition of the skin, the treatment area, and the desired outcome. Afterward, the results can be maintained with 1–2 treatments per year.
Are polynucleotides safe?
Both REJURAN® and PLINEST® are certified products used in aesthetic medicine. Before treatment, we always conduct a consultation during which we assess your skin, your health, and the suitability of the procedure. We only recommend treatment when it makes sense for your skin.
Can polynucleotides be combined with other procedures?
Yes. Polynucleotides can be combined, for example, with hyaluronic acid, mesotherapy, laser treatments, or other regenerative procedures. We always recommend a suitable combination on a case-by-case basis, depending on the condition of the skin and the goal of the treatment.
Are polynucleotides also effective for acne scars?
Yes. Polynucleotides can promote skin regeneration and gradually improve the texture of acne scars or minor skin irregularities. For more pronounced scars, we often recommend combining them with other treatments that promote skin remodeling.